Things that tick me off.
Political commercials. Especially when some talking hypocrite berating his/her opponent or trumpeting his/her own virtues wraps up by saying, "I'm Joe Blow, and I approve this message." No. Really? The fact that you were just in the commercial and were the one doing the talking wasn't enough for us to figure out that you approve it?
Legos. Not the Legos themselves, they can certainly be a lot of fun, but the idiots who decide that Legos are for construction, or art, or science, or some kind of numbskull application and they recreate the Mona Lisa out of Legos, or they build a quarter scale Statue of Liberty out of them in their backyard. Get a life. Perfect Example -> Aircraft Carrier.
Experts. When reading the newspaper, there are often statements such as "experts say" or "experts tell us" but there is no mention of who these idiots are. And, when does one become an "expert" anyway? Do you need a Doctorate, 25 years of experience, a letter from your mother?
Evolution. Seems to be a given fact these days that Evolution is gospel (sorry for the contradictory comparison) and all of the masses of asses just accept the "science" that we somehow showed up on this planet out of happenstance and started fighting with each other. It seems obvious to me that someone has to really be ignorant to believe in Evolution. But, I suppose it is easier than the alternative: We are sentient beings with a spirit and soul and a mission and are actually responsible for our actions.
Global Warming. If Global warming is such a crisis, how come my last 5 summers in a row have been so miserable? Colder than normal, no sun, miserable. If you believe the news, it seems like everything causes Global Warming these days, just like everything causes cancer. We're doomed anyway, so quit complaining.
Polls. Political polls should be outlawed. When these pollsters hit the road to try to find out what the average guy on the street thinks, they are trying to influence public opinion. Polls don't indicate what is going to happen, they shape people's opinions and can change what would have happened had people actually done the thinking for themselves.
Public Opinion. When one sees folks on the street being interviewed about their "views" of Obama's or McCain's policies and they start spouting off about foreign policy or domestic policy or healthcare, am I really supposed to think that this is important or valuable? Who are these losers anyway? I really don't care what someone outside of a HyVee grocery store thinks about the Financial Crisis.
Celebrities. It annoys me to no end to hear some multi-millionaire spout about their superior opinions on anything. Just because you have been in a movie or released a CD or been on television doesn't make anything you have to say any more interesting or important. Please just shut up. And, if you want to threaten to move out of the United States if this or that politician is elected (Michael Stipe), just go ahead and do it already ... nobody really actually cares.
Drugs. Watching television these days gives one the impression that everything about his/her life is insufficient, broken, inferior and that there is a drug which will help you sleep, lose weight, feel happy, have better sex, cure your restless leg syndrome, etc. Everybody, please just be silently miserable like all of the stoic generations before you. And, wake up, a pill won't solve your weight problem, but this small piece of advice might, "PUT DOWN THE FORK!"
Abbreviations. LOL, BRB, AFAIK, ROTFLOL, get a grip. This is not clever, it is not hip, it is not cool, it is retarded. I really get incensed when someone liberally sprinkles LOL every few sentences. Are they really "laughing out loud"? Learn to type. Quit it with the stupid abbreviations.
Chainletter emails. Do not send me an email which says that I must send it on to 10 people within the next 30 minutes and something good will happen or alternatively trying to use the guilt-trip method of urging me to send it if I am patriotic/caring/good enough. Guess what? I delete it and put your email address in my spam filter.
Idiots who don't fact check. If you are about to send an email with unsubstantiated claims in it, and especially if there are those telltale signs that it has been altered before being sent to you (example: the names in the email are a different font/size/colour), check the facts first before you send it. Snopes is a good place to start. Just because you want to believe something is true does not mean that it is.
Not using Blind Carbon Copy (BCC:). If you are going to send out an email to a long list of email addresses, do yourself and them a favor by placing all of the email addresses in the BCC: address line and not in the To: line. This helps protect people's privacy and helps reduce Spam. This is especially important for you if you are going to send out one of those unsubstantiated emails mentioned above. If you do this and do not BCC all recipients and I am one of them, I will respond to the entire list with a harsh rebuke for the lack of fact-checking on your part. You have been warned.

